NMR-based diffusion pore imaging by double wave vector measurements.
نویسندگان
چکیده
One main interest of nuclear magnetic resonance (NMR) diffusion experiments is the investigation of boundaries such as cell membranes hindering the diffusion process. NMR diffusion measurements allow collecting the signal from the whole sample. This mainly eliminates the problem of vanishing signal at increasing resolution. It has been a longstanding question if, in principle, the exact shape of closed pores can be determined by NMR diffusion measurements. In this work, we present a method using short diffusion gradient pulses only, which is able to reveal the shape of arbitrary closed pores without relying on a priori knowledge. In comparison to former approaches, the method has reduced demands on relaxation times due to faster convergence to the diffusion long-time limit and allows for a more flexible NMR sequence design, because, e.g., stimulated echoes can be used.
منابع مشابه
A general framework to quantify the effect of restricted diffusion on the NMR signal with applications to double pulsed field gradient NMR experiments.
Based on a description introduced by Robertson, Grebenkov recently introduced a powerful formalism to represent the diffusion-attenuated NMR signal for simple pore geometries such as slabs, cylinders, and spheres analytically. In this work, we extend this multiple correlation function formalism by allowing for possible variations in the direction of the magnetic field gradient waveform. This ex...
متن کاملNoninvasive bipolar double-pulsed-field-gradient NMR reveals signatures for pore size and shape in polydisperse, randomly oriented, inhomogeneous porous media.
Noninvasive characterization of pore size and shape in opaque porous media is a formidable challenge. NMR diffusion-diffraction patterns were found to be exceptionally useful for obtaining such morphological features, but only when pores are monodisperse and coherently placed. When locally anisotropic pores are randomly oriented, conventional diffusion NMR methods fail. Here, we present a simpl...
متن کاملA Tensor Approach for Double Wave Vector Experiments on Microscopic Anisotropy
Double wave-vector experiments (DWV) [1] involving two diffusion-weightings applied successively in a single experiment have been shown to be successful for the investigation of tissue micro-structure [2,4]. For short mixing times τm between the two wave vectors, the cell or compartment size can be estimated and a theoretical description was provided in terms of a tensor model [3] generalizing ...
متن کاملThe displacement correlation tensor from double wave vector diffusion experiments encodes information about pore microstructure and ensemble properties
Introduction: Pulsed field gradient diffusion sequences with multiple diffusion encoding blocks have recently gained renewed interest in the magnetic resonance community. Some of the properties that appear promising in terms of applications are the ability to measure pore sizes, detect anisotropic pores in macroscopically isotropic media, and the enhancement of diffraction peaks [1-3]. Here we ...
متن کاملLow-cost Vector Network Analyzer for Biomedical Applications
A low-cost and portable vector network analyzer (VNA) which covered operating frequency between 1MHz to 3GHz is used for vector reflection coefficient and standing wave ratio (swr) of the various microstrip antennas. This paper presents measurements of various ultra wideband (uwb) microstrip antennas for applications in biomedical field. Selection of antenna is an important key for detection of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Magnetic resonance in medicine
دوره 70 3 شماره
صفحات -
تاریخ انتشار 2013